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Necrotizing Soft Tissue Infections
A necrotizing soft tissue infection may result from aerobic or anaerobic organism and often occurs after a trauma, surgical procedure and/or around foreign body.  As the infection develops and increases, it decreases the level of oxygen to the area of injury.  As an adjunct therapy to debridement and antibiotics, HBO adversely affects the growth of anaerobic bacterial growth.

Radiation Necrosis
Radiation Necrosis is a tissue injury caused by radiation therapy for cancer. One of the complications from radiation is damage to tissue, there is loss of oxygen due to lack of blood supply.  Osteoradionecrosis is when the bone has been injured also.

When only muscle and skin is injured then it is referred to as soft tissue radionecrosis, hyperbaric oxygen therapy has been shown to stimulate growth of functioning capillaries and provide a better healing environment.

Hyperbaric oxygen therapy has also been used to treat radiation injury to other parts of the body, such as bladder, bowels, brain and chest.

Osteomyelitis is an infection of the bone that is usually caused by bacteria and can be chronic or acute. It can be a result of a bacterial bloodstream infection or occur from a nearby infection due to a traumatic injury.  Refractory osteomyelitis is a bone infection which has not responded to suitable treatment.  Hyperbaric Oxygen increases the oxygen level in the infected area which helps promote healing in the hypoxic tissues, and is used as an adjunctive therapy with appropriate antibiotics, debridement, surgery and nutrition.

Actinomycosis is a bacteria infection that most often occurs in the face and neck and is characterized by the presence of a slowly enlarging, hard, red lump.  It is difficult to treat due to the dense tissue location.  Actinomycosis israelii is an anaerobic bacterium which means it dislikes oxygen but grows very well in deep tissues were oxygen levels are low.  Surgery is often required followed by antibiotic.   Hyperbaric oxygen therapy in combination with the antibiotic therapy has been successful in treating this condition.

Periodonitis is the advanced stage of gum disease, the early stage being referred to as gingivitis.  If left untreated the gums become irritated and can lead to bleeding and in the more severe cases loss of teeth.  Combined with correct dental care hyperbaric oxygen therapy helps in the healing process and reduction of gum swelling, possibly preventing tooth loss.

Oral & Maxillofacial
Hyperbaric oxygen therapy is used in maxillofacial (jaw and neck) surgical patients in their healing process after injury, trauma or disease. Studies have shown that patients have healed faster with less wound complications following their surgery or procedures.